Across TCGA patient cohorts, ZNF479 mutation is significantly associated with the total protein of many other genes, with 64 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF479-associated genes across cancer lineages are Akt_pT308, GAPDH, and ATM. Each is linked with ZNF479 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF479-to-partner and partner-to-ZNF479 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF479→partner) and Y-score (partner→ZNF479) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Akt_pT308 →	+0.399	+1.999	.038	.008	3	4
SKCM	GAPDH →	+0.442	+1.662	.032	.011	3	3
UCEC	ATM →	-0.603	-2.308	<.001	<.001	3	3
LUAD	4E-BP1_pS65 →	+0.168	+1.713	<.001	.024	3	2
LUSC	Heregulin →	-0.178	-3.584	.010	.002	3	2
LUSC	MYH11 →	-0.694	-3.000	.038	.033	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 64 associations by consensus.

Exploration

ZNF479 survival (RNA) · tumor vs normal (RNA) · all ZNF479 data types