ZNF474

Across TCGA patient cohorts, ZNF474 RNA expression is significantly associated with the RNA expression of many other genes, with 18,042 significant associations in total. UVM shows the largest number of these associations.

The most reproducible ZNF474-associated genes across cancer lineages are ZNF474-AS1, AFF4, and TTC37. Each is linked with ZNF474 in more than 28 cancer types. Because this analysis shows association rather than direction, both ZNF474-to-partner and partner-to-ZNF474 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF474 versus ZNF474-AS1 in UCEC, with a Pearson correlation of 0.89.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF474→partner) and Y-score (partner→ZNF474) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZNF474-AS1 →	+1.703	+1.900	<.001	<.001	3	29
UVM	AFF4 →	+1.257	+0.134	<.001	<.001	3	28
UVM	TTC37 →	+1.445	+0.137	<.001	<.001	3	27
BRCA	KIAA0825 →	+0.517	+0.361	<.001	<.001	3	27
DLBC	CPLANE1 →	+0.883	+0.182	<.001	<.001	3	26
UCS	RASA1 →	+1.293	+1.229	<.001	<.001	3	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,042 associations by consensus.

ZNF474 vs ZNF474-AS1 — UCEC

Explore this scatter interactively →