ZNF474

Across TCGA patient cohorts, ZNF474 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,366 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ZNF474-associated proteins across cancer lineages are NME7, BBS7, and TPPP3. Each is linked with ZNF474 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF474-to-partner and partner-to-ZNF474 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF474 versus NME7 in UCEC, with a Pearson correlation of 0.66.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF474→partner) and Y-score (partner→ZNF474) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NME7 →	+0.327	+1.565	<.001	<.001	3	6
UCEC	BBS7 →	+0.394	+1.489	<.001	<.001	3	6
UCEC	TPPP3 →	+1.889	+1.889	<.001	<.001	3	5
LUAD	TPPP3_S162 →	+1.376	+0.984	<.001	.001	3	5
LSCC	UBXN10_S87 →	+1.280	+0.860	<.001	<.001	3	5
UCEC	BBS2 →	+0.518	+1.609	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,366 associations by consensus.

ZNF474 vs NME7 — UCEC

Explore this scatter interactively →