ZNF473

Across TCGA patient cohorts, ZNF473 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,604 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF473-associated proteins across cancer lineages are LIG1, UBE2M, and TRIM28. Each is linked with ZNF473 in more than 8 cancer types. Because this analysis shows association rather than direction, both ZNF473-to-partner and partner-to-ZNF473 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF473 versus LIG1 in BRCA, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF473→partner) and Y-score (partner→ZNF473) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LIG1 →	+0.537	+0.404	<.001	<.001	3	9
BRCA	UBE2M →	+0.357	+0.544	<.001	<.001	3	7
GBM	TRIM28 →	+0.466	+0.502	<.001	<.001	3	7
OV	PNKP →	+0.322	+0.537	<.001	.001	3	7
BRCA	PRMT1 →	+0.397	+0.677	<.001	<.001	3	7
OV	HSPBP1 →	+0.315	+0.466	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,604 associations by consensus.

ZNF473 vs LIG1 — BRCA

Explore this scatter interactively →