ZNF473

Across TCGA patient cohorts, ZNF473 mutation is significantly associated with the RNA expression of many other genes, with 3,161 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF473-associated genes across cancer lineages are RPL34P19, MIR4757, and ALDOA. Each is linked with ZNF473 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF473-to-partner and partner-to-ZNF473 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL34P19 grouped by ZNF473-low versus ZNF473-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF473→partner) and Y-score (partner→ZNF473) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RPL34P19 →	+0.133	+5.268	<.001	.006	3	3
LIHC	MIR4757 →	+0.508	+6.305	<.001	.001	3	3
UCEC	ALDOA →	+0.453	+2.662	<.001	<.001	3	3
UCEC	TMEM11 →	+0.390	+2.131	<.001	<.001	3	3
COAD	CNOT7P1 →	+0.223	+3.474	.002	.006	3	3
UCEC	LMF2 →	+0.446	+4.321	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,161 associations by consensus.

RPL34P19 by ZNF473 expression — LIHC

Explore this box plot interactively →