ZNF473

Across TCGA cell cohorts, ZNF473 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,300 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZNF473-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Constitutive heterochromatin formation, and Regulation of DNA repair. Each is linked with ZNF473 in more than 14 cancer types. Because this analysis shows association rather than direction, both ZNF473-to-partner and partner-to-ZNF473 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by ZNF473-low versus ZNF473-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF473→partner) and Y-score (partner→ZNF473) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Epigenetic regulation of gene expression →	+0.066	+0.574	.004	.005	3	15
BONE	Constitutive heterochromatin formation →	+0.101	+0.831	.001	.002	3	14
BONE	Regulation of DNA repair →	+0.081	+0.708	.001	.002	3	13
BONE	DNA-templated transcription elongation →	+0.070	+0.703	.002	.001	3	13
SOFT_TISSUE	Heterochromatin formation →	+0.065	+0.879	<.001	<.001	3	13
BONE	RNA catabolic process →	+0.062	+0.698	.001	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,300 associations by consensus.

Epigenetic regulation of gene expression by ZNF473 expression — BONE

Explore this box plot interactively →