Across TCGA patient cohorts, ZNF471 mutation is significantly associated with the RNA expression of many other genes, with 2,656 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF471-associated genes across cancer lineages are NDUFAF1, TUBGCP5, and CENPU. Each is linked with ZNF471 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF471-to-partner and partner-to-ZNF471 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF471→partner) and Y-score (partner→ZNF471) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NDUFAF1 →	+0.392	+1.917	<.001	<.001	3	4
UCEC	TUBGCP5 →	+0.307	+2.010	.004	.005	3	3
UCEC	CENPU →	+0.484	+1.517	.004	.002	3	3
UCEC	PANK4 →	+0.323	+2.140	<.001	.002	3	3
UCEC	ZNF367 →	+0.503	+1.485	.002	.003	3	3
UCEC	SHCBP1 →	+0.442	+2.753	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,656 associations by consensus.

Exploration

ZNF471 survival (RNA) · tumor vs normal (RNA) · all ZNF471 data types