Across TCGA patient cohorts, ZNF471 mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF471-associated genes across cancer lineages are FASN, FoxM1, and Ku80. Each is linked with ZNF471 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF471-to-partner and partner-to-ZNF471 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF471→partner) and Y-score (partner→ZNF471) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FASN →	+0.407	+1.765	.001	.013	3	2
UCEC	FoxM1 →	+0.182	+1.523	.027	.008	3	2
UCEC	Ku80 →	+0.224	+1.302	.003	.015	3	2
UCEC	MEK1 →	+0.281	+2.169	.016	.003	3	2
UCEC	Notch1 →	+0.158	+1.424	<.001	.027	3	2
UCEC	p62 Lck ligand →	+0.372	+2.378	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

ZNF471 survival (RNA) · tumor vs normal (RNA) · all ZNF471 data types