Across TCGA cell cohorts, ZNF471 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF471-associated genes across cancer lineages are HIGD1C, CBLN4, and REG1B. Each is linked with ZNF471 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF471-to-partner and partner-to-ZNF471 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF471→partner) and Y-score (partner→ZNF471) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	HIGD1C →	+0.108	+5.201	<.001	.006	3	1
BLOOD_Leukemia	CBLN4 →	+0.006	+5.539	<.001	.003	3	1
LARGE_INTESTINE	REG1B →	+2.047	+3.196	.001	.007	3	1
LARGE_INTESTINE	HIGD2B →	+0.060	+3.724	<.001	.004	2	1
LARGE_INTESTINE	GCGR →	+0.128	+3.584	.008	.006	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

ZNF471 survival (RNA) · tumor vs normal (RNA) · all ZNF471 data types