ZNF470

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ZNF470 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ZNF470 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher ZNF470 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF470 expression acts as an unfavorable survival marker.

UCS, CESC, and ESCA are the cancer types where ZNF470 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCSOSMedianII,III,IV0.0010.616<.00124view →
CESCOSMedianAll0.0980.587.00712view →
ESCAOSMedianAll0.2070.911.00112view →
BLCAOSMedianIV0.1890.603.0023view →
LIHCOSMedianAll0.1670.704.0413view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration