Across TCGA patient cohorts, ZNF470 mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF470-associated genes across cancer lineages are C-Raf, EGFR_pY1068, and PCNA. Each is linked with ZNF470 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF470-to-partner and partner-to-ZNF470 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF470→partner) and Y-score (partner→ZNF470) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	C-Raf →	+0.108	+1.584	.016	.017	3	3
UCEC	EGFR_pY1068 →	-0.190	-2.222	.015	.009	3	2
UCEC	PCNA →	+0.233	+2.662	<.001	<.001	3	2
UCEC	Shc_pY317 →	-0.153	-1.353	.001	.015	3	2
UCEC	Smad1 →	+0.107	+1.137	.030	.041	3	2
UCEC	14-3-3_beta →	-0.093	-1.571	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

ZNF470 survival (RNA) · tumor vs normal (RNA) · all ZNF470 data types