Across TCGA cell cohorts, ZNF470 mutation is significantly associated with the RNA expression of many other genes, with 85 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF470-associated genes across cancer lineages are PIP, OR2T35, and CA2. Each is linked with ZNF470 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF470-to-partner and partner-to-ZNF470 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF470→partner) and Y-score (partner→ZNF470) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	PIP →	+0.040	+4.807	<.001	.006	3	1
BLOOD_Myeloma	OR2T35 →	+0.086	+4.807	<.001	.006	3	1
LARGE_INTESTINE	CA2 →	+1.668	+3.502	.002	.001	3	1
LARGE_INTESTINE	ASPN →	+0.048	+3.793	<.001	<.001	3	1
LARGE_INTESTINE	MYH3 →	+0.723	+3.064	<.001	.009	3	1
LARGE_INTESTINE	NDUFC1 →	+0.604	+3.502	.003	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 85 associations by consensus.

Exploration

ZNF470 survival (RNA) · tumor vs normal (RNA) · all ZNF470 data types