Across TCGA cell cohorts, ZNF469 mutation is significantly associated with the RNA expression of many other genes, with 1,307 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF469-associated genes across cancer lineages are MMS19, CDCA8, and PLK4. Each is linked with ZNF469 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF469-to-partner and partner-to-ZNF469 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF469→partner) and Y-score (partner→ZNF469) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	MMS19 →	+0.492	+3.303	.005	.004	2	4
LARGE_INTESTINE	CDCA8 →	+0.448	+3.252	.003	.002	3	3
LARGE_INTESTINE	PLK4 →	+0.721	+2.130	<.001	<.001	3	3
LARGE_INTESTINE	H2AZ1 →	+0.679	+2.130	<.001	<.001	3	3
BREAST	C17orf49 →	+0.849	+2.372	.001	.009	3	3
SKIN	NEK2 →	+0.661	+3.321	.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,307 associations by consensus.

Exploration

ZNF469 survival (RNA) · tumor vs normal (RNA) · all ZNF469 data types