Across TCGA patient cohorts, ZNF468 mutation is significantly associated with the RNA expression of many other genes, with 3,540 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF468-associated genes across cancer lineages are MIR6894, MIR6803, and TAF9. Each is linked with ZNF468 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF468-to-partner and partner-to-ZNF468 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF468→partner) and Y-score (partner→ZNF468) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR6894 →	+0.541	+5.506	<.001	.005	3	3
LUAD	MIR6803 →	+0.561	+5.798	<.001	.003	3	3
UCEC	TAF9 →	+0.726	+2.115	<.001	<.001	3	2
UCEC	RWDD1 →	+0.597	+1.922	<.001	<.001	3	2
SKCM	CWC15 →	+0.624	+3.353	.009	.005	3	2
CESC	RN7SKP263 →	+0.058	+4.247	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,540 associations by consensus.

Exploration

ZNF468 survival (RNA) · tumor vs normal (RNA) · all ZNF468 data types