Across TCGA patient cohorts, ZNF468 mutation is significantly associated with the total protein of many other genes, with 38 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF468-associated genes across cancer lineages are GAPDH, mTOR_pS2448, and PDCD4. Each is linked with ZNF468 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF468-to-partner and partner-to-ZNF468 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF468→partner) and Y-score (partner→ZNF468) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GAPDH →	+0.484	+1.662	.010	.011	3	2
UCEC	mTOR_pS2448 →	-0.139	-2.794	.008	.003	3	2
UCEC	PDCD4 →	-0.653	-2.000	<.001	.003	3	2
UCEC	ATM →	-0.636	-3.794	<.001	<.001	3	2
UCEC	Caspase-7-cleavedD198 →	+0.491	+1.604	.019	.041	3	2
UCEC	Chk2_pT68 →	-0.138	-2.295	.036	.033	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 38 associations by consensus.

Exploration

ZNF468 survival (RNA) · tumor vs normal (RNA) · all ZNF468 data types