Across TCGA cell cohorts, ZNF468 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,522 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF468-associated GO terms across cancer lineages are Negative regulation of mRNA metabolic process, Regulation of organelle assembly, and Chromosomal 5-methylcytosine DNA demethylation pathway. Each is linked with ZNF468 in more than 9 cancer types. Because this analysis shows association rather than direction, both ZNF468-to-partner and partner-to-ZNF468 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF468→partner) and Y-score (partner→ZNF468) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Negative regulation of mRNA metabolic process →	+0.061	+0.681	<.001	.004	3	10
BONE	Regulation of organelle assembly →	+0.039	+1.069	<.001	.002	3	9
UPPER_AERODIGESTIVE_TRACT	Chromosomal 5-methylcytosine DNA demethylation pathway →	+0.116	+1.819	.004	<.001	3	9
CNS	Golgi vesicle transport →	+0.047	+0.751	<.001	<.001	3	9
LUNG_SCLC	Vesicle coating →	+0.105	+1.414	<.001	.002	3	9
LUNG_SCLC	Vacuolar transport →	+0.062	+1.228	<.001	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,522 associations by consensus.

Exploration

ZNF468 survival (RNA) · tumor vs normal (RNA) · all ZNF468 data types