Across TCGA cell cohorts, ZNF468 mutation is significantly associated with the RNA expression of many other genes, with 726 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF468-associated genes across cancer lineages are MTMR3, TNRC6B, and POLR3H. Each is linked with ZNF468 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF468-to-partner and partner-to-ZNF468 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF468→partner) and Y-score (partner→ZNF468) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MTMR3 →	+0.657	+3.212	.006	.006	3	1
LARGE_INTESTINE	TNRC6B →	+0.847	+3.212	<.001	.006	3	1
LARGE_INTESTINE	POLR3H →	+1.008	+3.212	<.001	.006	3	1
LARGE_INTESTINE	FZD3 →	+1.130	+3.212	<.001	.006	3	1
LARGE_INTESTINE	KDELR1 →	+0.548	+3.212	.003	.006	3	1
LARGE_INTESTINE	OCIAD1 →	+0.513	+3.212	.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 726 associations by consensus.

Exploration

ZNF468 survival (RNA) · tumor vs normal (RNA) · all ZNF468 data types