Across TCGA cell cohorts, ZNF468 mutation is significantly associated with the mutation status of many other genes, with 5,409 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF468-associated genes across cancer lineages are COL14A1, CHL1, and APBA1. Each is linked with ZNF468 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF468-to-partner and partner-to-ZNF468 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF468→partner) and Y-score (partner→ZNF468) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	COL14A1 →	+4.044	+5.000	.008	.008	1	4
LUNG_NSCLC_LUAD	CHL1 →	+3.924	+5.063	.001	.001	1	4
CNS	APBA1 →	+4.459	+5.277	.005	.005	1	4
CNS	CCT8L2 →	+5.044	+5.614	.003	.003	1	3
LUNG_NSCLC_LUAD	TSSK1B →	+5.339	+4.772	.004	.004	1	3
SKIN	SLF2 →	+5.392	+4.824	.004	.004	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,409 associations by consensus.

Exploration

ZNF468 survival (RNA) · tumor vs normal (RNA) · all ZNF468 data types