ZNF462

Across TCGA patient cohorts, ZNF462 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,359 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF462-associated proteins across cancer lineages are ZNF462_S2172, STAG2, and NCF1. Each is linked with ZNF462 in more than 8 cancer types. Because this analysis shows association rather than direction, both ZNF462-to-partner and partner-to-ZNF462 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF462 versus ZNF462_S2172 in BRCA, with a Pearson correlation of 0.71.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF462→partner) and Y-score (partner→ZNF462) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZNF462_S2172 →	+0.925	+0.917	<.001	<.001	3	9
GBM	STAG2 →	+0.312	+0.655	<.001	<.001	3	6
CCRCC	NCF1 →	-0.497	-0.595	.005	.002	3	6
BRCA	NFIX →	+0.477	+0.762	<.001	<.001	3	6
BRCA	ZNF462_S2169 →	+1.208	+1.510	<.001	<.001	3	6
CCRCC	PTPN1 →	-0.453	-0.804	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,359 associations by consensus.

ZNF462 vs ZNF462_S2172 — BRCA

Explore this scatter interactively →