ZNF462

Across TCGA patient cohorts, ZNF462 protein abundance is significantly associated with the RNA expression of many other genes, with 16,567 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF462-associated genes across cancer lineages are GPR161, IL17RD, and SNHG30. Each is linked with ZNF462 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF462-to-partner and partner-to-ZNF462 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF462 versus GPR161 in HNSC, with a Pearson correlation of 0.28.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF462→partner) and Y-score (partner→ZNF462) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	GPR161 →	+0.767	+0.440	.003	.004	3	5
CCRCC	IL17RD →	+1.459	+0.403	<.001	<.001	3	5
LSCC	SNHG30 →	+0.518	+0.385	<.001	<.001	3	5
LSCC	KIAA1549 →	+1.035	+0.335	<.001	<.001	3	4
BRCA	CDK8 →	+0.748	+0.508	<.001	.001	3	4
OV	MKRN1 →	+0.473	+0.542	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,567 associations by consensus.

ZNF462 vs GPR161 — HNSC

Explore this scatter interactively →