Across TCGA patient cohorts, ZNF461 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,368 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF461-associated proteins across cancer lineages are SAE1, TRIM28, and UBA2. Each is linked with ZNF461 in more than 5 cancer types. Because this analysis shows association rather than direction, both ZNF461-to-partner and partner-to-ZNF461 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF461→partner) and Y-score (partner→ZNF461) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SAE1 →	+0.343	+0.452	<.001	<.001	3	6
LSCC	TRIM28 →	+0.386	+0.503	<.001	.001	3	6
GBM	UBA2 →	+0.302	+0.469	<.001	<.001	3	6
LSCC	TAF6L →	+0.305	+0.559	<.001	.001	3	5
PDAC	TBCB →	+0.403	+0.474	<.001	<.001	3	5
LSCC	ARID4B →	+0.254	+0.428	<.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,368 associations by consensus.

Exploration

ZNF461 survival (RNA) · tumor vs normal (RNA) · all ZNF461 data types