Across TCGA cell cohorts, ZNF461 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF461-associated genes across cancer lineages are ZC2HC1B, KRTAP2-1, and R3HDML. Each is linked with ZNF461 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF461-to-partner and partner-to-ZNF461 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF461→partner) and Y-score (partner→ZNF461) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	ZC2HC1B →	+0.090	+3.632	<.001	.009	3	1
BLOOD_Lymphoma	KRTAP2-1 →	+0.064	+4.643	<.001	.005	3	1
BLOOD_Leukemia	R3HDML →	+0.020	+5.569	<.001	.001	3	1
BLOOD_Leukemia	PIP →	+0.048	+4.705	.008	.003	3	1
BLOOD_Leukemia	OR56A1 →	+0.074	+4.276	<.001	.007	3	1
BLOOD_Leukemia	SCGB1C1 →	+0.104	+4.539	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

ZNF461 survival (RNA) · tumor vs normal (RNA) · all ZNF461 data types