Across TCGA pan-cancer cohorts, ZNF460 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ZNF460 data layer compared with 23 for mass-spec protein and 3 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ZNF460 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF460 expression acts as an unfavorable survival marker.

KIRC and LIHC are the cancer types where ZNF460 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.122	0.811	<.001	36	view →
LIHC	DFS	Median	All	0.094	0.555	.002	12	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: ZNF460 tumor-vs-normal RNA expression · all ZNF460 data types