Across TCGA patient cohorts, ZNF460 mutation is significantly associated with the RNA expression of many other genes, with 2,076 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF460-associated genes across cancer lineages are RPL7AP72, RNU4-75P, and RNA5SP411. Each is linked with ZNF460 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF460-to-partner and partner-to-ZNF460 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF460→partner) and Y-score (partner→ZNF460) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RPL7AP72 →	+0.063	+5.435	.007	.005	3	3
STAD	RNU4-75P →	+0.750	+4.691	<.001	.003	3	3
UCEC	RNA5SP411 →	+1.109	+1.978	<.001	.002	3	2
READ	OR6K5P →	+0.057	+6.257	<.001	.001	3	2
READ	RN7SL578P →	+0.172	+5.039	<.001	.008	3	2
READ	SNX18P23 →	+0.078	+5.653	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,076 associations by consensus.

Exploration

ZNF460 survival (RNA) · tumor vs normal (RNA) · all ZNF460 data types