Across TCGA cell cohorts, ZNF460 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,065 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF460-associated GO terms across cancer lineages are RNA destabilization, mRNA destabilization, and Positive regulation of mRNA metabolic process. Each is linked with ZNF460 in more than 15 cancer types. Because this analysis shows association rather than direction, both ZNF460-to-partner and partner-to-ZNF460 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF460→partner) and Y-score (partner→ZNF460) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	RNA destabilization →	+0.094	+0.934	<.001	<.001	3	16
LUNG_NSCLC_LUSC	mRNA destabilization →	+0.098	+1.131	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mRNA metabolic process →	+0.074	+0.735	.001	.002	3	16
OESOPHAGUS	Regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.073	+0.718	.003	.002	2	16
BONE	miRNA processing →	+0.106	+0.842	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Positive regulation of mRNA catabolic process →	+0.077	+0.854	.001	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,065 associations by consensus.

Exploration

ZNF460 survival (RNA) · tumor vs normal (RNA) · all ZNF460 data types