Across TCGA cell cohorts, ZNF460 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF460-associated genes across cancer lineages are C3orf56, EDDM3B, and ECE2. Each is linked with ZNF460 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF460-to-partner and partner-to-ZNF460 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF460→partner) and Y-score (partner→ZNF460) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	C3orf56 →	+0.006	+4.977	<.001	.007	3	1
STOMACH	EDDM3B →	+0.033	+5.285	<.001	.003	3	1
LARGE_INTESTINE	ECE2 →	+0.345	+4.054	<.001	.004	3	1
LARGE_INTESTINE	USP17L7 →	+0.089	+3.691	<.001	.009	2	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

ZNF460 survival (RNA) · tumor vs normal (RNA) · all ZNF460 data types