ZNF45

Across TCGA patient cohorts, ZNF45 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,429 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF45-associated proteins across cancer lineages are TRIM28, SAE1, and XRCC1. Each is linked with ZNF45 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNF45-to-partner and partner-to-ZNF45 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF45 versus TRIM28 in GBM, with a Pearson correlation of 0.70.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF45→partner) and Y-score (partner→ZNF45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TRIM28 →	+0.494	+0.549	<.001	<.001	3	7
GBM	SAE1 →	+0.449	+0.478	<.001	<.001	3	7
HNSC	XRCC1 →	+0.308	+0.855	<.001	<.001	3	6
BRCA	PPP5C →	+0.280	+0.647	<.001	<.001	3	6
LUAD	IRGQ →	+0.351	+0.565	<.001	<.001	3	6
GBM	IRF2BP1 →	+0.386	+0.521	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,429 associations by consensus.

ZNF45 vs TRIM28 — GBM

Explore this scatter interactively →