ZNF45

Across TCGA cell cohorts, ZNF45 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,875 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ZNF45-associated GO terms across cancer lineages are Positive regulation of organelle assembly, Regulation of microtubule-based process, and Protein localization to chromosome. Each is linked with ZNF45 in more than 16 cancer types. Because this analysis shows association rather than direction, both ZNF45-to-partner and partner-to-ZNF45 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of organelle assembly grouped by ZNF45-low versus ZNF45-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF45→partner) and Y-score (partner→ZNF45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of organelle assembly →	+0.069	+0.893	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Regulation of microtubule-based process →	+0.047	+0.606	.003	.004	2	16
SOFT_TISSUE	Protein localization to chromosome →	+0.090	+0.865	<.001	<.001	3	15
SOFT_TISSUE	Negative regulation of cell cycle process →	+0.065	+0.879	<.001	<.001	3	14
BONE	Microtubule polymerization →	+0.107	+0.570	.004	.007	3	14
BLOOD_Lymphoma	Nuclear envelope organization →	+0.067	+0.900	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,875 associations by consensus.

Positive regulation of organelle assembly by ZNF45 expression — STOMACH

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