Across TCGA patient cohorts, ZNF445 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,231 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF445-associated proteins across cancer lineages are QRICH1, TOP2B, and RBM15B. Each is linked with ZNF445 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNF445-to-partner and partner-to-ZNF445 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF445→partner) and Y-score (partner→ZNF445) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	QRICH1 →	+0.221	+0.432	<.001	<.001	3	7
GBM	TOP2B →	+0.478	+0.624	<.001	<.001	3	7
GBM	RBM15B →	+0.333	+0.681	<.001	<.001	3	6
GBM	TRIM28 →	+0.365	+0.417	<.001	<.001	3	6
BRCA	S100A8 →	-1.664	-0.574	<.001	<.001	3	6
GBM	KIAA1143 →	+0.364	+0.526	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,231 associations by consensus.

Exploration

ZNF445 survival (RNA) · tumor vs normal (RNA) · all ZNF445 data types