ZNF442

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF442 mutation is significantly associated with the total protein of many other genes, with 46 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF442-associated genes across cancer lineages are TFRC, ATM, and Caspase-7-cleavedD198. Each is linked with ZNF442 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF442-to-partner and partner-to-ZNF442 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF442→partner) and Y-score (partner→ZNF442) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMTFRC →+0.667+3.000.036.03632
UCECATM →-0.595-1.906<.001<.00132
UCECCaspase-7-cleavedD198 →+0.521+1.756.002.00332
UCECc-Met_pY1235 →+0.062+1.726.004.00132
UCECCyclin-B1 →+0.694+2.146<.001<.00132
SKCM14-3-3_epsilon →+0.223+3.017.001.01932
Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

Exploration