Across TCGA patient cohorts, ZNF441 protein abundance is significantly associated with the RNA expression of many other genes, with 173 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF441-associated genes across cancer lineages are GZMB, EEF1A2, and KLF5. Each is linked with ZNF441 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF441-to-partner and partner-to-ZNF441 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF441→partner) and Y-score (partner→ZNF441) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GZMB →	+1.100	+0.550	.006	<.001	3	1
UCEC	EEF1A2 →	+0.273	+0.549	.005	<.001	3	1
UCEC	KLF5 →	+2.686	+0.683	.006	.004	3	1
UCEC	TMEM59L →	+0.275	+0.549	.003	<.001	3	1
UCEC	UPK2 →	+1.470	+0.716	.001	.002	3	1
UCEC	ACRBP →	+0.652	+0.550	.004	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 173 associations by consensus.

Exploration

ZNF441 survival (RNA) · tumor vs normal (RNA) · all ZNF441 data types