Across TCGA patient cohorts, ZNF441 mutation is significantly associated with the RNA expression of many other genes, with 3,031 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF441-associated genes across cancer lineages are MIR4510, MIR649, and TUBBP11. Each is linked with ZNF441 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF441-to-partner and partner-to-ZNF441 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF441→partner) and Y-score (partner→ZNF441) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR4510 →	+0.297	+5.342	<.001	.002	3	2
CESC	MIR649 →	+0.532	+4.705	<.001	.003	3	2
COAD	TUBBP11 →	+0.284	+5.087	<.001	.002	3	2
UCEC	SLC25A27 →	-0.583	-2.654	.001	<.001	3	2
UCEC	TMEM251 →	+0.427	+1.864	.002	.004	3	2
UCEC	MFSD12 →	+0.362	+2.254	.003	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,031 associations by consensus.

Exploration

ZNF441 survival (RNA) · tumor vs normal (RNA) · all ZNF441 data types