Across TCGA cell cohorts, ZNF441 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF441-associated genes across cancer lineages are TMIGD1, HELT, and SMIM28. Each is linked with ZNF441 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF441-to-partner and partner-to-ZNF441 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF441→partner) and Y-score (partner→ZNF441) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	TMIGD1 →	+0.028	+4.169	<.001	.008	3	1
CNS	HELT →	+0.030	+4.321	<.001	.009	3	1
CNS	SMIM28 →	+0.034	+4.321	.004	.009	3	1
BLOOD_Lymphoma	CSTL1 →	+0.621	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	ZNF735 →	+0.098	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	OR4M2 →	+0.031	+4.867	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

ZNF441 survival (RNA) · tumor vs normal (RNA) · all ZNF441 data types