ZNF44

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF44 mutation is significantly associated with the total protein of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF44-associated genes across cancer lineages are PKC-b-II_pS660, ATM, and RAD51. Each is linked with ZNF44 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF44-to-partner and partner-to-ZNF44 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF44→partner) and Y-score (partner→ZNF44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPKC-b-II_pS660 →-0.230-1.584.010.01733
UCECATM →-0.625-2.893<.001.00133
COADRAD51 →+0.168+3.178.030.01024
UCECeEF2 →+0.265+2.459.022.01832
UCECeIF4E →+0.185+2.321.006<.00132
UCECFoxM1 →+0.203+2.584.015.01032
Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

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