Across TCGA cell cohorts, ZNF44 mutation is significantly associated with the RNA expression of many other genes, with 73 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF44-associated genes across cancer lineages are SSMEM1, FBXW10, and OR12D2. Each is linked with ZNF44 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF44-to-partner and partner-to-ZNF44 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF44→partner) and Y-score (partner→ZNF44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SSMEM1 →	+0.021	+2.707	.001	.003	3	2
LARGE_INTESTINE	FBXW10 →	+0.263	+3.491	<.001	.004	3	2
LARGE_INTESTINE	OR12D2 →	+0.047	+2.560	<.001	.008	3	2
BLOOD_Leukemia	VWC2L →	+0.013	+3.339	<.001	.006	3	2
LUNG_NSCLC_LUSC	GAGE12J →	+0.266	+4.643	<.001	.008	3	1
SOFT_TISSUE	OR10Q1 →	+0.167	+4.930	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 73 associations by consensus.

Exploration

ZNF44 survival (RNA) · tumor vs normal (RNA) · all ZNF44 data types