Across TCGA cell cohorts, ZNF44 mutation is significantly associated with the mutation status of many other genes, with 5,600 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF44-associated genes across cancer lineages are CHD7, PLXNA3, and F5. Each is linked with ZNF44 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF44-to-partner and partner-to-ZNF44 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF44→partner) and Y-score (partner→ZNF44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	CHD7 →	+2.284	+2.866	.003	.003	1	5
PANCREAS	PLXNA3 →	+5.257	+5.257	<.001	<.001	1	4
BLOOD_Leukemia	F5 →	+3.341	+3.341	.001	.001	1	4
SKIN	CLCN5 →	+4.239	+5.053	.007	.007	1	4
LARGE_INTESTINE	PITPNM2 →	+1.757	+2.278	.008	.008	1	4
SOFT_TISSUE	ITGAL →	+5.066	+4.502	.007	.007	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,600 associations by consensus.

Exploration

ZNF44 survival (RNA) · tumor vs normal (RNA) · all ZNF44 data types