ZNF439

Across TCGA cell cohorts, ZNF439 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,878 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF439-associated GO terms across cancer lineages are Regulation of post-translational protein modification, Regulation of protein modification by small protein conjugation or removal, and Regulation of mitotic metaphase/anaphase transition. Each is linked with ZNF439 in more than 10 cancer types. Because this analysis shows association rather than direction, both ZNF439-to-partner and partner-to-ZNF439 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of post-translational protein modification grouped by ZNF439-low versus ZNF439-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF439→partner) and Y-score (partner→ZNF439) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of post-translational protein modification →	+0.062	+1.444	<.001	.001	3	11
STOMACH	Regulation of protein modification by small protein conjugation or removal →	+0.064	+1.415	<.001	<.001	3	11
SOFT_TISSUE	Regulation of mitotic metaphase/anaphase transition →	+0.129	+2.187	<.001	<.001	3	11
SOFT_TISSUE	Regulation of sister chromatid segregation →	+0.128	+2.128	<.001	<.001	3	11
SOFT_TISSUE	Regulation of metaphase/anaphase transition of cell cycle →	+0.126	+2.238	<.001	<.001	3	11
STOMACH	Regulation of DNA-templated transcription initiation →	+0.075	+1.788	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,878 associations by consensus.

Regulation of post-translational protein modification by ZNF439 expression — LUNG_NSCLC_LUSC

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