ZNF439

Across TCGA cell cohorts, ZNF439 mutation is significantly associated with the drug of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF439-associated genes across cancer lineages are 123829, FTY-720, and PRT062607. Each is linked with ZNF439 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF439-to-partner and partner-to-ZNF439 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 123829 grouped by ZNF439-low versus ZNF439-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF439→partner) and Y-score (partner→ZNF439) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	123829 →	+0.578	+2.649	.048	.046	3	1
LARGE_INTESTINE	FTY-720 →	+0.214	+2.722	.037	.040	3	1
LARGE_INTESTINE	PRT062607 →	+0.658	+2.769	.008	.040	2	1
LARGE_INTESTINE	GSK2110183B →	+0.708	+2.649	.019	.046	2	1
LARGE_INTESTINE	Teniposide →	+0.565	+2.649	.034	.046	1	1
LARGE_INTESTINE	AT7867 →	+0.544	+2.652	.023	.045	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

123829 by ZNF439 expression — LARGE_INTESTINE

Explore this box plot interactively →