Across TCGA patient cohorts, ZNF438 protein abundance is significantly associated with the RNA expression of many other genes, with 1,811 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ZNF438-associated genes across cancer lineages are FADS6, ATP6V1H, and NDUFB2. Each is linked with ZNF438 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF438-to-partner and partner-to-ZNF438 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF438→partner) and Y-score (partner→ZNF438) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FADS6 →	-0.794	-0.333	.003	.004	3	2
CCRCC	ATP6V1H →	-0.463	-0.321	<.001	.001	3	2
PDAC	NDUFB2 →	-0.411	-0.337	<.001	.006	3	2
CCRCC	HMOX1 →	-0.899	-0.282	<.001	.001	3	1
CCRCC	EIF3D →	+0.244	+0.309	.004	.001	3	1
CCRCC	CERK →	+0.516	+0.277	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,811 associations by consensus.

Exploration

ZNF438 survival (RNA) · tumor vs normal (RNA) · all ZNF438 data types