Across TCGA patient cohorts, ZNF438 mutation is significantly associated with the RNA expression of many other genes, with 4,062 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF438-associated genes across cancer lineages are ABALON, CDK2, and BOLA2-SMG1P6. Each is linked with ZNF438 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF438-to-partner and partner-to-ZNF438 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF438→partner) and Y-score (partner→ZNF438) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ABALON →	+0.522	+1.925	<.001	<.001	3	3
SKCM	CDK2 →	+0.863	+2.141	.005	.009	3	3
UCEC	BOLA2-SMG1P6 →	+0.403	+1.925	.003	<.001	3	3
UCEC	CENPI →	+0.474	+2.023	.001	.005	3	3
UCEC	NEIL3 →	+0.549	+2.338	<.001	<.001	3	3
UCEC	RFC5 →	+0.675	+3.258	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,062 associations by consensus.

Exploration

ZNF438 survival (RNA) · tumor vs normal (RNA) · all ZNF438 data types