Across TCGA patient cohorts, ZNF433 mutation is significantly associated with the RNA expression of many other genes, with 2,462 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF433-associated genes across cancer lineages are RNU6-54P, RNA5SP414, and RNA5SP411. Each is linked with ZNF433 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF433-to-partner and partner-to-ZNF433 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF433→partner) and Y-score (partner→ZNF433) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RNU6-54P →	+0.514	+6.608	<.001	.001	3	3
BRCA	RNA5SP414 →	+0.477	+8.471	<.001	.005	3	2
UCEC	RNA5SP411 →	+0.656	+1.461	.003	.009	3	2
BRCA	RNA5SP422 →	+0.865	+8.055	<.001	.007	3	2
BRCA	RNA5SP416 →	+0.725	+8.471	<.001	.005	3	2
CESC	RNU6-961P →	+0.184	+4.020	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,462 associations by consensus.

Exploration

ZNF433 survival (RNA) · tumor vs normal (RNA) · all ZNF433 data types