ZNF433

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF433 mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF433-associated genes across cancer lineages are mTOR_pS2448, Notch1, and TIGAR. Each is linked with ZNF433 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF433-to-partner and partner-to-ZNF433 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF433→partner) and Y-score (partner→ZNF433) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECmTOR_pS2448 →-0.125-2.209.015.00932
UCECNotch1 →+0.194+2.459<.001<.00132
UCECTIGAR →+0.151+2.096.004.00132
UCECTSC1 →-0.119-2.282.045.03332
UCECCaspase-7-cleavedD198 →+0.779+1.827<.001.01532
UCECCyclin-B1 →+0.479+2.459.013.01832
Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration