ZNF432

Across TCGA cell cohorts, ZNF432 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible ZNF432-associated genes across cancer lineages are AVP, PGLYRP4, and FOXI2. Each is linked with ZNF432 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF432-to-partner and partner-to-ZNF432 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AVP grouped by ZNF432-low versus ZNF432-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF432→partner) and Y-score (partner→ZNF432) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	AVP →	+0.038	+5.209	<.001	.005	3	2
SOFT_TISSUE	PGLYRP4 →	+0.016	+5.369	<.001	.004	3	1
SOFT_TISSUE	FOXI2 →	+0.006	+4.930	<.001	.008	3	1
LARGE_INTESTINE	SERPINB12 →	+0.152	+3.823	<.001	.006	3	1
LARGE_INTESTINE	TECRL →	+0.017	+4.562	<.001	<.001	3	1
LARGE_INTESTINE	OR5V1 →	+0.008	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

AVP by ZNF432 expression — BLOOD_Lymphoma

Explore this box plot interactively →