Across TCGA patient cohorts, ZNF43 mutation is significantly associated with the RNA expression of many other genes, with 3,041 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF43-associated genes across cancer lineages are NARS1, TXNL4B, and RAD51. Each is linked with ZNF43 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF43-to-partner and partner-to-ZNF43 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF43→partner) and Y-score (partner→ZNF43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	NARS1 →	+0.444	+2.933	.001	<.001	3	4
UCEC	TXNL4B →	+0.494	+1.784	<.001	<.001	3	4
UCEC	RAD51 →	+0.663	+2.010	<.001	<.001	3	4
UCEC	WDR76 →	+0.508	+2.301	<.001	<.001	3	4
UCEC	TUBGCP4 →	+0.502	+1.584	<.001	.001	3	4
SKCM	CCNQ →	+0.493	+3.497	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,041 associations by consensus.

Exploration

ZNF43 survival (RNA) · tumor vs normal (RNA) · all ZNF43 data types