Across TCGA cell cohorts, ZNF43 mutation is significantly associated with the RNA expression of many other genes, with 105 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF43-associated genes across cancer lineages are ADIG, TDGF1, and GRPEL1. Each is linked with ZNF43 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF43-to-partner and partner-to-ZNF43 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF43→partner) and Y-score (partner→ZNF43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	ADIG →	+0.267	+2.730	<.001	.008	3	2
CNS	TDGF1 →	+0.149	+3.938	<.001	<.001	3	2
LARGE_INTESTINE	GRPEL1 →	+0.491	+2.451	.002	.009	3	1
LARGE_INTESTINE	SDHB →	+0.489	+2.451	.003	.009	3	1
LARGE_INTESTINE	SERAC1 →	+0.625	+3.389	.002	.001	3	1
LARGE_INTESTINE	ATPAF1 →	+0.700	+3.502	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 105 associations by consensus.

Exploration

ZNF43 survival (RNA) · tumor vs normal (RNA) · all ZNF43 data types