Across TCGA patient cohorts, ZNF429 mutation is significantly associated with the RNA expression of many other genes, with 2,883 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF429-associated genes across cancer lineages are COX6B1P6, PEX11A, and ALDH18A1. Each is linked with ZNF429 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF429-to-partner and partner-to-ZNF429 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF429→partner) and Y-score (partner→ZNF429) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	COX6B1P6 →	+0.088	+3.549	<.001	.003	3	3
UCEC	PEX11A →	+0.414	+2.094	<.001	<.001	3	3
UCEC	ALDH18A1 →	+0.449	+3.711	<.001	<.001	3	3
STAD	MTND4LP22 →	+0.325	+3.941	.005	.001	3	3
HNSC	MIR3689F →	+0.355	+5.221	<.001	.003	3	3
UCEC	HMGCR →	+0.562	+2.917	.006	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,883 associations by consensus.

Exploration

ZNF429 survival (RNA) · tumor vs normal (RNA) · all ZNF429 data types