Across TCGA patient cohorts, ZNF429 mutation is significantly associated with the total protein of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF429-associated genes across cancer lineages are Mre11, Akt_pS473, and p53. Each is linked with ZNF429 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF429-to-partner and partner-to-ZNF429 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF429→partner) and Y-score (partner→ZNF429) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Mre11 →	-0.082	-2.673	.002	.005	3	2
UCEC	Akt_pS473 →	+0.485	+1.765	.034	.013	3	2
UCEC	p53 →	-0.275	-1.289	.026	.023	3	2
UCEC	Akt_pT308 →	+0.495	+1.523	.013	.008	3	2
UCEC	PCNA →	+0.193	+1.906	.005	.015	3	2
UCEC	S6_pS240_S244 →	+0.498	+2.058	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

Exploration

ZNF429 survival (RNA) · tumor vs normal (RNA) · all ZNF429 data types