Across TCGA cell cohorts, ZNF429 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,974 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF429-associated GO terms across cancer lineages are Regulation of double-strand break repair, Negative regulation of chromatin organization, and Regulation of heterochromatin formation. Each is linked with ZNF429 in more than 9 cancer types. Because this analysis shows association rather than direction, both ZNF429-to-partner and partner-to-ZNF429 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF429→partner) and Y-score (partner→ZNF429) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Regulation of double-strand break repair →	+0.057	+1.538	<.001	<.001	3	10
LUNG_SCLC	Negative regulation of chromatin organization →	+0.135	+1.205	.001	.004	3	9
LUNG_SCLC	Regulation of heterochromatin formation →	+0.179	+1.751	<.001	<.001	3	9
BREAST	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.169	+1.856	<.001	<.001	3	9
BREAST	Regulation of nucleotide-excision repair →	+0.108	+1.256	.002	.004	3	8
SOFT_TISSUE	Tubulin deacetylation →	+0.083	+0.709	.009	.007	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,974 associations by consensus.

Exploration

ZNF429 survival (RNA) · tumor vs normal (RNA) · all ZNF429 data types