Across TCGA cell cohorts, ZNF429 mutation is significantly associated with the RNA expression of many other genes, with 26 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF429-associated genes across cancer lineages are CYP7A1, KRTAP2-1, and KRTAP2-2. Each is linked with ZNF429 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF429-to-partner and partner-to-ZNF429 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF429→partner) and Y-score (partner→ZNF429) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	CYP7A1 →	+0.017	+4.191	<.001	.007	3	1
BLOOD_Lymphoma	KRTAP2-1 →	+0.064	+4.643	<.001	.005	3	1
BLOOD_Lymphoma	KRTAP2-2 →	+0.060	+5.247	<.001	.001	3	1
BLOOD_Lymphoma	RD3L →	+0.099	+4.191	<.001	.007	3	1
BLOOD_Lymphoma	PSG11 →	+0.097	+4.714	<.001	.002	3	1
BREAST	SLC17A2 →	+0.010	+4.781	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

Exploration

ZNF429 survival (RNA) · tumor vs normal (RNA) · all ZNF429 data types