ZNF428

Across TCGA patient cohorts, ZNF428 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,105 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF428-associated proteins across cancer lineages are PAFAH1B3, ANXA1, and MBD3. Each is linked with ZNF428 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF428-to-partner and partner-to-ZNF428 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF428 versus PAFAH1B3 in OV, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF428→partner) and Y-score (partner→ZNF428) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PAFAH1B3 →	+0.442	+0.694	.001	<.001	3	5
GBM	ANXA1 →	-0.571	-0.380	<.001	<.001	3	4
GBM	MBD3 →	+0.534	+0.605	<.001	<.001	3	4
OV	SMARCD1 →	+0.466	+0.797	<.001	<.001	3	4
LSCC	NANS →	-0.319	-0.477	<.001	.001	3	4
OV	IRGQ →	+0.367	+0.560	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,105 associations by consensus.

ZNF428 vs PAFAH1B3 — OV

Explore this scatter interactively →